Background. Data on mental disorders, manifesting in Hodgkin's disease patients are rather limited. Such disorders are considered as within somatogenic psychoses and adjustment disorders. Among described psychoses identified isolated cases of delusional disorders, delirium, oneiric. Among the adjustment disorders described is mainly anxiety, depression, or combinations thereof. Systematic studies of psychiatric disorders in patients with Hodgkin's disease have not been conducted. Aim. To identify the structure of mental disorders in patients with Hodgkin's disease. Material and methods. There were examined 95 patients with Hodgkin's disease by clinical-psychopathological method. Results of the study were subjected to statistical analysis using Stat for Windows 5.5 licensing programs. Results and discussion. It was revealed that endogenomorphical psychoses (hallucinatory-paranoid and depressive-delusional states) and somatogenically provoked schizophrenia attacks in Hodgkin's disease patients are much more likely (17 and 6, respectively) than delirium, unlike other hematological malignancies, in which be present (or was found observed) the opposite trends. In addition, Hodgkin's disease is the only hematological malignancy in the studied sample, in which the schizophrenia attacks are detected (were detected). Among adjustment disorders in Hodgkin's disease patients were identified as follows: anxiety and dissociative (n = 29) (anxiety and dissociative reactions occur with symptoms of the phenomenon of alienation of real hematological disease and signs of latent somatization of anxiety, accompanied by abnormal behavior in the disease), hypomanic (n = 4), dissociative (n = 25) (dominated by the phenomenon of alienation of the hematological malignancy, reaching the degree of total denial of the fact of the blood system diseases, revealed gross cognitive disorders characterized by distinct partial peculiar syndrome pseudodementia) and anxiety-koenestopathical (n = 14) (somatogenically and / or psychogenic provoked polymorphic functional symptoms, abnormal bodily sensations). Conclusion. The study results show that in a sample of Hodgkin's disease patients schizoid spectrum disorders accumulate, what could serve as a reason for further studies of this phenomenon, involving both clinical and biological research methods.